CAIASoft has two relevant item information pieces for circulation purposes - item state and item flags.
The flags are actually more relevant for circulation behavior - I was getting them confused in my head. Anyway, I'll put information on this page from Duke's implementation of CAIASoft this past spring.
Item State
At Duke so far we appear to have mainly used these for reporting purposes, but we're early on and I know that we want to be able to use the Restrict Circulation option. In other words, if we mark an item as Restrict Circulation for PYR, it should not be able to be pulled for a FOLIO circulation request.
Please, others who know more about CAIASoft (or even Laura Beatham,) they should also review this to make sure what I am saying is correct.